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• Health economics
• Economic evaluation methodology and application, particularly alongside randomised controlled trials
• Outcome measurement including non-monetary preference-based methods
• Special interest in the economics of dermatology, falls prevention, rehabilitation, public health and primary care
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I am an experienced collaborator, leading the health economic aspects within numerous NIHR funded clinical trials. Open to new collaborations.

Current on-going projects include: 

Patient Involvement in Health Economics Research (Award ID: NIHR306648). Sach TH, Al-Janabi H, Bauer A, Hawton A, Henaghan-Sykes K, Kandiyali R, McCloskey S, Istry K, Perry S, Purtell R, Ruthen P, Staniszewska S.  Team Science award Round 2: October 2025 to March 2027: £98,952.

Optimising Maternal and Perinatal Death Surveillance and Response to prevent future deaths (Award ID: NIHR156746). Willcox M, Manu A, Agga M, Akweongo P, Okong P, Tura AK, Kharono B, Murokora D, Namgembe I, Issah K, Kinney M, Islam N, Nakibuuka V, Mubangizi V, Ewunetie S, Palestra F,  Mbuo M, Ameh C, Jackson D, Kabakyenga J, Torpey K, Knight M, van den Akker T, Sach T. NIHR Global Health Research Units and Groups, July 2024 – July 2028, £3,025,777.

 Preventing food allergy in infants with early introduction of complementary feeding (Award ID: NIHR206263). Roberts G, Ainsworth B, Venter C, Khaleva E, Muller I,  Michaelis LJ, Marino L, Lee P, Easton S, Williams S, Buttery J, Dixon S, Larsson M, Cook A,  Santer M, Sach T.    NIHR Programme Grants for Applied Research, Sept 2024-Sept 2029, £2,936,971.

PHarmacy partnership using decision-making tools and near patient testing for Antimicrobial Stewardship for EveryDay practice IN primary care (Award ID: NIHR158312). Little P, Lown M, Muller I, Hand K, Tonkin-Crine S, Becque T, Richards-Hall S, Bond C, Butler C, Garner C, Griffiths G, Raftery J, Yardley L, Francis N, de Lusignan S, Latter S, Sach T. NIHR HSDR, Sept 2023- Feb 2025, £859,740.

Antibiotics for acute lower respiratory tract infection in older people (Award ID: NIHR157478). Lown M, Francis N, Little P, Griffiths G, Conroy S, Becque T, Sach T, Verheij T, Ogden M, Kumar R. NIHR HTA, £1,700,532.

Proactive against reactive therapy for the prevention of lichen sclerosus exacerbation and progression of disease – a pragmatic parallel group randomised controlled trial with embedded economic evaluation and process evaluation (PEARLS)(Award ID: NIHR135121). Simpson R, Thomas K, Daniels J, McPherson T, Sivalingam V, Rees S, Hillman S, Sach T, Ogollah R, Sudhakaran S, Baumhauner C, Norman E. NIHR HTA, 57 months, £1,636,175.

Investigating the benefits and harms of reduced daily dose oral isotretinoin in the treatment of acne: A parallel group, assessor blind, non-inferiority, multicentre randomised controlled trial, with an internal pilot (AcneID)(Award ID: NIHR151318). Burden-Teh E, Thomas K, Ravenscroft J, Williams H, Healy E, Layton A, Santer M, Northover G, Radley K, Mitchell E, Hepburn T, Leighton P, Sach T, Thompson A, Ramesh G, Leng S. NIHR HTA, 60 months, £2,148,574.06.

Cellulitis Optimal Antibiotic Treatment: COAT study (Award ID: NIHR134867). Francis N, Santer M, Thomas K, Levell N, Little P, Stuart B, Nuttall J, Read R, Sach T. NIHR HTA, 48 months, £1,476,575.

Developing and testing an online intervention to support self-management, improve outcomes and reduce antibiotic use in acne (Award ID: NIHR202852). Santer M, Muller I, Stuart B, Thomas K, Layton A, Little P, Yardley L, Francis N, Ridd M, Sach T. Langan S, Soulsby I, Patel M, Dove S, Griffiths G, Thompson A.  NIHR Programme Grants for Applied Research, £1,901,577.

Best systemic treatments for adults with atopic eczema over the long term (BEACON): A randomised, assessor-blind trial comparing ciclosporin, methotrexate and dupilumab (Award ID: NIHR129926). Smith C, Pink A, Chalmers J, Emsley R, Williams H, Parmar M, Sach T, Reynolds N, Smith S, Murphy C, Cape A, Kelly J, Burton T, Dougans A, Kelly J, Proctor A. NIHR HTA Programme, 48 months, £1,899,852

I am also providing health economic input into the following NIHR funded studies:

REducing Common infections in Usual practice for Recurrent Respiratory tract infections. (RECUR)(Award ID: RP-PG-0218-20005). Led by Professor Paul Little, NIHR Programme Grants for Applied Research, £2,462,362.

Development of a mixed (reusable/disposable)catheter management package for users of intermittent catheterization (Award ID: RP-PG-0610-10078). Led by Professor Mandy Fader, NIHR Programme Grants for Applied Research, £2,786,093.

The development and iMplementation Of a multidisciplinary medication review and Deprescribing Intervention among Frail older people in primarY care (feasibility study WP4). Led by Dr Kinda Ibrahim, ARC Wessex.